More on calcium ion activity buffers for coagulation testing.
نویسنده
چکیده
terpreted as postovulatory luteal phase rather than follicular. Assuming a 2.2 mg/L positive bias with SST, our current laboratory follicular phase progesterone reference range of ,1.6 mg/L could increase to ,3.8 mg/L with SST. We recommend that all progesterone serum samples be collected in plain glass tubes until this SST interference problem is resolved. Our laboratory has notified Roche Diagnostics of this finding.
منابع مشابه
Isocitrate as calcium ion activity buffer in coagulation assays.
BACKGROUND Ca(2+) activity close to the physiological concentration of 1.3 mmol/L is essential in blood coagulation. Is this also true for the performance of global diagnostic coagulation assays? We searched for compounds that would buffer Ca(2+) activity at approximately 1.3 mmol/L without disturbing coagulation reactions and investigated whether such Ca(2+) buffering improves diagnostic effic...
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The activation of factor VIII:C by thrombin appears to be an important prerequisite for the function of factor VIII:C as a cofactor in factor X activation in coagulation. The possible modulation of factor VIII:C activation by potential cofactors such as calcium ions, phospholipid, and platelets was studied systematically. Factor VIII:C activation could not be studied in the complete absence of ...
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عنوان ژورنال:
- Clinical chemistry
دوره 45 9 شماره
صفحات -
تاریخ انتشار 1999